When PCOS progresses to insulin resistance, relying solely on oral medications may not suffice. At this stage, Ayurvedic treatments like Udwartana, Virechana, and Basti are introduced to address the metabolic imbalances and correct insulin resistance. These therapies, combined with tailored diet and lifestyle modifications, offer a comprehensive approach to managing PCOS in patients with insulin resistance, promoting improved outcomes and long-term well-being.