Arthritis, or Santhi Gata Vata in Ayurveda, is the inflammation of joints and their related structures, or rather the localization of Vata entity in the joints (Sandhi). This occurs as a result of diminished digestive fire (Agni) culminating in the accumulation of metabolic toxins(Ama). Arthritis or degenerative joint disease are terms used to describe the loss of cartilage in the affected joints.